Date: Wednesday, 26 June 2024
Time: 15:00 - 16:00 CEST
Session code 3CV.6
Biorefineries processes and integration
Exploring Xylose Transport Genes from Candida Tropicalis for Enhanced Biomass Conversion in Bioprocesses
Short Introductive summary
The use of lignocellulosic biomass as a raw material in industrial bioprocesses is a promising strategy in the context of the circular economy. Specifically focusing on the hemicellulosic fraction, the deconstruction of this macromolecule results in hydrolysates rich in pentoses (C5), particularly xylose. However, Saccharomyces cerevisiae, one of the most widely used yeasts in industrial fermentation processes, is inefficient in assimilating xylose. Genetic engineering efforts aim to overcome this limitation, developing S. cerevisiae strains efficient in xylose bioconversion. Although improvements have been observed through the heterologous expression of Xylose Reductase (XR), Xylitol Dehydrogenase (XDH), and other enzymes of the pentose phosphate pathway in S. cerevisiae, optimal efficiency in xylose bioconversion requires the presence of transport proteins responsible for the assimilation and internalization of xylose into the yeast cell. This study is focused on naturally occurring yeast species capable of metabolizing C5 sugars as a model for the identification and characterizing of pentose transporters, which can improve xylose utilization.
Presenter
Sarah DE SOUZA QUEIROZ
Technical University of Denmark
Biographies and Short introductive summaries are supplied directly by presenters and are published here unedited
Co-authors:
T. da Franca Silva, University of São Paulo, Lorena, BRAZIL
G. Henrique Goldman, University of São Paulo, Lorena, BRAZIL
M. das Graças de Almeida Felipe, University of São Paulo, Lorena, BRAZIL
S. Inês Mussatto, Technical University of Denmark, Kongens Lyngby, DENMARK
Session reference: 3CV.6.14